Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633418 | 0.87 | TSHR (0.71) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL944028 | 0.87 | TSHR (0.71) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL2027590 | 0.86 | TSHR (0.71) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL1959525 | 0.86 | TSHR (0.69) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113301 | 0.85 | TSHR (0.62) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18873252 | 0.84 | TSHR (0.67) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL9219368 | 0.84 | TSHR (0.67) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL11633750 | 0.83 | TSHR (0.61) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113159 | 0.83 | TSHR (0.65) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| Diethyl Phthalate SCHEMBL22296 | 0.82 | TSHR (1.00) | TSHRALDH1A1HSD17B10LMNACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001019684-A | DERIVATIVE OF 1,2-BENZISOTHIAZOLIN-3-ONE AND ITS PREPARATION | AGENCY OF IND SCIENCE & TECHNOL | 2001-01-23 | — | — | JP | disclosed |