Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757054 | 0.92 | CYP3A4 (0.50) | KDM4EMAPTMAPK1LMNAPKM | |
| SCHEMBL7754180 | 0.92 | KDM4E (0.50) | KDM4EMAPTMAPK1LMNAPKM | |
| SCHEMBL7751068 | 0.88 | TYR (0.50) | KDM4EMAPTHTTALOX5TSHR | |
| SCHEMBL7755513 | 0.86 | ESR1 (0.50) | KDM4EMAPTHTTALOX5TSHR | |
| SCHEMBL7755725 | 0.84 | CYP3A4 (0.47) | KDM4EMAPTHTTALOX5TSHR | |
| SCHEMBL27449392 | 0.84 | KDM4E (0.59) | KDM4EMAPTMAPK1LMNAPKM | |
| Hydrochloric Acid SCHEMBL4743941 | 0.82 | KDM4E (0.50) | KDM4EMAPTMAPK1LMNAPKM | |
| SCHEMBL7754618 | 0.82 | ESR1 (0.55) | KDM4EMAPTLMNAHTTALOX5 | |
| SCHEMBL5694415 | 0.80 | CYP19A1 (0.48) | KDM4EMAPTMAPK1LMNAPKM | |
| SCHEMBL7755696 | 0.79 | KMT2A (0.48) | KDM4EMAPTLMNAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811595-B1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI CHEMICALS INC (JP) | 2001-02-07 | — | — | EP | disclosed |
| US-5880314-A | DEPIGMENTING; SAFE TO SKIN, STORAGE STABLE | MITSUI CHEMICALS, INC. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811595-A1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-12-10 | — | — | EP | disclosed |