Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751072 | 1.00 | KDM2B (0.41) | KDM2BHDAC3HDAC1HDAC2EPHX2 | |
| SCHEMBL7751078 | 1.00 | KDM2B (0.41) | KDM2BHDAC3HDAC1HDAC2EPHX2 | |
| SCHEMBL7754667 | 1.00 | KDM2B (0.41) | KDM2BHDAC3HDAC1HDAC2EPHX2 | |
| SCHEMBL7757066 | 0.89 | KMT2A (0.40) | ALDH1A1MAPTSMN1; SMN2CYP2C9LMNA | |
| SCHEMBL7757062 | 0.89 | KMT2A (0.40) | ALDH1A1MAPTSMN1; SMN2CYP2C9LMNA | |
| SCHEMBL7754704 | 0.87 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2CYP2C9LMNA | |
| SCHEMBL7754699 | 0.87 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2CYP2C9LMNA | |
| SCHEMBL7755760 | 0.87 | ESRRG (0.37) | KDM2BHDAC3HDAC1HDAC2EPHX2 | |
| SCHEMBL7757079 | 0.87 | ESRRG (0.37) | KDM2BHDAC3HDAC1HDAC2EPHX2 | |
| SCHEMBL7755762 | 0.87 | ESRRG (0.37) | KDM2BHDAC3HDAC1HDAC2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |