Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754681 | 1.00 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2IDO1ALDH1A1 | |
| SCHEMBL7755539 | 1.00 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2IDO1ALDH1A1 | |
| SCHEMBL7755541 | 1.00 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2IDO1ALDH1A1 | |
| SCHEMBL7754704 | 0.89 | MAPT (0.50) | KMT2ASMN1; SMN2ALDH1A1MAPTDRD2 | |
| SCHEMBL7754699 | 0.89 | MAPT (0.50) | KMT2ASMN1; SMN2ALDH1A1MAPTDRD2 | |
| SCHEMBL7757062 | 0.88 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7757066 | 0.88 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7754484 | 0.87 | MAPT (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7754496 | 0.87 | MAPT (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7757034 | 0.87 | MAPT (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |