SCHEMBL7755485

SCHEMBL7755485

CCC(C)(C)c1ccc(OC(C)CC([NH])=O)c(C(C)(C)CC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.52
NPSR1 Q6W5P4 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 4/20 0.40
HTT P42858 3/20 0.40
UBE2N P61088 2/20 0.40
GLA P06280 1/20 0.40
MITF O75030 1/20 0.40
RAB9A P51151 3/20 0.37
RAD52 P43351 2/20 0.37
STAT3 P40763 1/20 0.37
RCE1 Q9Y256 1/20 0.37
APAF1 O14727 1/20 0.37
HSP90AA1 P07900 1/20 0.37
NOD2 Q9HC29 1/20 0.37
NPC1 O15118 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755491 0.87 MAPK1 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10857954 0.87 MAPK1 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10706504 0.84 MAPK1 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5489761 0.82 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9768526 0.82 MAPK1 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL75843 0.81 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28378701 0.80 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8980027 0.80 MAPK1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7227225 0.79 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10634380 0.79 MAPK1 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751427-B1 Image-dye-forming couplers and photographic elements containing them EASTMAN KODAK CO (US) 2001-03-28 EP disclosed
EP-0751428-B1 Novel image-dye-forming couplers and photographic elements containing them KODAK LTD (GB) 1999-10-06 EP disclosed
US-5962208-A Silver halide color photographic material containing a yellow coupler and a mercapto compound FUJI PHOTO FILM CO., LTD. (JP) 1999-10-05 US disclosed
US-5693458-A THIENYLCARBONYLACETANILIDE DERIVATIVES; CONTRAST; PHOTOSTABILITY; STORAGE AND WET STABILITY; EASTMAN KODAK COMPANY (US) 1997-12-02 US disclosed
EP-0529992-B1 Silver halide color photographic material KONISHIROKU PHOTO IND (JP) 1997-11-05 EP disclosed
US-5674667-A COLORFASTNESS; CONTRAST EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
EP-0472153-B1 A silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-03-05 EP disclosed
EP-0751428-A1 Novel image-dye-forming couplers and photographic elements containing them KODAK LIMITED (GB) 1997-01-02 EP disclosed
EP-0751427-A1 Image-dye-forming couplers and photographic elements containing them KODAK LIMITED (GB) 1997-01-02 EP disclosed
EP-0326406-B1 Silver halide photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1995-11-08 EP disclosed
US-5112728-A Hydroxyphenyl-Benzotriazole UV Absorber, Magenta Coupler KONICA CORPORATION (JP) 1992-05-12 US disclosed
EP-0472153-A1 A silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1992-02-26 EP disclosed
US-5066574-A Hydantoin derivatives KONICA CORPORATION (JP) 1991-11-19 US disclosed
EP-0422513-A2 A silver halide photographic light-sensitive material containing a novel yellow coupler KONICA CORPORATION (JP) 1991-04-17 EP disclosed
EP-0192471-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1990-08-08 EP disclosed
US-4945034-A Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1990-07-31 US disclosed
US-4868100-A IMPROVED COLOR REPRODUCTIBILITY KONICA CORPORATION (JP) 1989-09-19 US disclosed
EP-0326406-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1989-08-02 EP disclosed
US-4710453-A PYRAZOLOTRIAZOLE YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-12-01 US disclosed
EP-0192471-A2 Silver halide color photographic material KONICA CORPORATION (JP) 1986-08-27 EP disclosed