Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755488 | 1.00 | MAPT (0.46) | MAPTSMN1; SMN2SPHK1THRBTHRA | |
| SCHEMBL7751084 | 1.00 | MAPT (0.46) | MAPTSMN1; SMN2SPHK1THRBTHRA | |
| SCHEMBL7751083 | 1.00 | MAPT (0.46) | MAPTSMN1; SMN2SPHK1THRBTHRA | |
| SCHEMBL7757034 | 0.92 | MAPT (0.43) | MAPTSMN1; SMN2THRB | |
| SCHEMBL7757037 | 0.92 | MAPT (0.43) | MAPTSMN1; SMN2THRB | |
| SCHEMBL7754496 | 0.92 | MAPT (0.43) | MAPTSMN1; SMN2THRB | |
| SCHEMBL7754484 | 0.92 | MAPT (0.43) | MAPTSMN1; SMN2THRB | |
| SCHEMBL11292835 | 0.85 | MAPT (0.50) | MAPTSMN1; SMN2SPHK1THRBTHRA | |
| SCHEMBL7754704 | 0.85 | MAPT (0.50) | MAPTSMN1; SMN2 | |
| SCHEMBL7754699 | 0.85 | MAPT (0.50) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |