Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167075 | 0.90 | CHRM2 (0.73) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL4398908 | 0.85 | CHRM2 (0.48) | CHRM2CHRM1MAPTCES2 | |
| SCHEMBL2166659 | 0.85 | CHRM2 (0.74) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL7580032 | 0.85 | CHRM2 (0.68) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL7756404 | 0.81 | CHRM2 (0.48) | CHRM2CHRM1FAAHLMNAMAPT | |
| SCHEMBL6759380 | 0.81 | CHRM2 (0.60) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL4659036 | 0.79 | CHRM2 (0.51) | CHRM2CHRM1MAPT | |
| SCHEMBL4660409 | 0.79 | CHRM2 (0.51) | CHRM2CHRM1MAPT | |
| SCHEMBL2169511 | 0.79 | CHRM2 (0.70) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL7555814 | 0.79 | CHRM2 (0.82) | CHRM2CHRM1CHRM3ADRB2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |