SCHEMBL7755669

SCHEMBL7755669

CO/C=C(/Oc1cccc(COc2ccc(C#N)cc2)c1C(=O)OC(C)(C)C)C(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 6/20 0.36
NR1H3 Q13133 6/20 0.36
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
RXRA P19793 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
PTGER4 P35408 1/20 0.34
SMPD1 P17405 1/20 0.33
RAB9A P51151 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
SCN9A Q15858 1/20 0.33
AR P10275 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755672 1.00 NR1H2 (0.36) NR1H2NR1H3CYP11B1CYP11B2RXRA
SCHEMBL7749529 0.91 NR1H2 (0.38) NR1H2NR1H3RXRARAB9AMRGPRX4
SCHEMBL7749531 0.91 NR1H2 (0.38) NR1H2NR1H3RXRARAB9AMRGPRX4
SCHEMBL7749565 0.90 NR1H2 (0.38) NR1H2NR1H3RXRA
SCHEMBL7749562 0.90 NR1H2 (0.38) NR1H2NR1H3RXRA
SCHEMBL7754455 0.89 NR1H2 (0.39) NR1H2NR1H3RXRAPTGER4
SCHEMBL7754457 0.89 NR1H2 (0.39) NR1H2NR1H3RXRAPTGER4
SCHEMBL7749510 0.89 KDM4E (0.37) NR1H2NR1H3RXRAL3MBTL1RAB9A
SCHEMBL7749507 0.89 KDM4E (0.37) NR1H2NR1H3RXRAL3MBTL1RAB9A
SCHEMBL7753222 0.88 PTGER4 (0.41) CYP11B1CYP11B2L3MBTL1PTGER4SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010029239-A1 New herbicidal compositions CRAMP MICHAEL COLIN (GB) 2001-10-11 US disclosed
WO-2001047863-A2 NEW HERBICIDAL COMPOSITIONS AVENTIS CROPSCIENCE SA (FR) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010029239-A1 New herbicidal compositions DDT, CYP1B1, CYP4X1 NR1H2 1849/4885NR1H3 2372/4885CYP11B1 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.