⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37331 | 0.76 | — | — | |
| SCHEMBL37332 | 0.76 | — | — | |
| SCHEMBL3921048 | 0.75 | — | — | |
| SCHEMBL7124693 | 0.74 | — | — | |
| SCHEMBL11595765 | 0.71 | KDM1A (0.43) | — | |
| SCHEMBL11595763 | 0.71 | KDM1A (0.43) | — | |
| SCHEMBL3922472 | 0.70 | — | — | |
| SCHEMBL1767300 | 0.70 | — | — | |
| SCHEMBL3394744 | 0.70 | — | — | |
| SCHEMBL1767298 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597333-B1 | Compounds for fluoroscense polarization immunoassays and immunoassays utilising them | HOFFMANN LA ROCHE (CH) | 2001-02-28 | — | — | EP | disclosed |
| US-5315015-A | Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same | HOFFMANN-LA ROCHE INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0597333-A2 | Compounds for fluoroscense polarization immunoassays and immunoassays utilising them | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-18 | — | — | EP | disclosed |
| US-4255329-A | QUALITATIVE AND QUANTITATIVE ANALYSIS; SENSITIVITY; SPECTROPHOTOMERY | SYVA COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4161515-A | DETECTING ANTILIGAND WITH LIGAND-ANALOG FLUORESCER | SYVA COMPANY (US) | 1979-07-17 | — | — | US | disclosed |