SCHEMBL7755735

SCHEMBL7755735

CCCC1CCC(c2ccc(-c3ccc(C4CC[SiH](CCC)CC4)cc3)c(F)c2)CC1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.41
CYP3A4 P08684 4/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
APP P05067 2/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
FASN P49327 1/20 0.36
ESR2 Q92731 3/20 0.35
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8447753 1.00 CYP2C9 (0.41) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL8771327 1.00 CYP2C9 (0.41) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL8420386 1.00 CYP2C9 (0.41) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL7755729 1.00 CYP2C9 (0.41) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL8420387 1.00 CYP2C9 (0.41) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL7753108 0.92 CYP2C9 (0.39) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL8420237 0.92 CYP3A4 (0.38) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL8032320 0.92 CYP2C9 (0.39) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL7753111 0.92 CYP2C9 (0.39) CYP2C9CYP3A4ALDH1A1LMNAMAPT
SCHEMBL8420593 0.92 CYP3A4 (0.38) CYP2C9CYP3A4ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718387-B1 A liquid crystal composition and a liquid crystal display element which contains it SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
EP-0659753-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 1999-09-22 EP disclosed
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed
EP-0799878-A1 Liquid crystal compositions and liquid crystal display elements containing same Shin-Etsu Chemical Co., Ltd. (JP) 1997-10-08 EP disclosed
US-5573705-A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-11-12 US disclosed
EP-0718387-A1 A liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-26 EP disclosed
EP-0659753-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-06-28 EP disclosed