Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680150 | 0.93 | PTPN11 (0.46) | PTPN11RARBNPC1SMN1; SMN2NFKB1 | |
| SCHEMBL7760968 | 0.85 | PTPN11 (0.44) | PTPN11RARBTHRANPC1ALDH1A1 | |
| SCHEMBL6676195 | 0.85 | PTPN11 (0.37) | PTPN11RARBNPC1SMN1; SMN2NFKB1 | |
| SCHEMBL6681424 | 0.81 | PTPN11 (0.53) | PTPN11RARBLMNATP53TSHR | |
| SCHEMBL19484788 | 0.78 | MAPT (0.43) | PTPN11NPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6681432 | 0.78 | PTPN11 (0.46) | PTPN11RARBNPC1ALDH1A1RAB9A | |
| SCHEMBL5546811 | 0.78 | PTPN11 (0.46) | PTPN11RARBNPC1ALDH1A1RAB9A | |
| SCHEMBL28215172 | 0.76 | BACE1 (0.58) | NPC1SMN1; SMN2KDM4EALDH1A1NFKB1 | |
| SCHEMBL28090830 | 0.74 | NR5A1 (0.49) | PTPN11THRANPC1ALDH1A1RAB9A | |
| SCHEMBL7759691 | 0.74 | NR1H4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089984-A1 | NON-YELLOWING PARA-TERTIARY-ALKYL PHENYL SUBSTITUTED TRIAZINE AND PYRIMIDINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067226-A1 | NON-YELLOWING PARA-TERTIARY-ALKYL PHENYL SUBSTITUTED TRIAZINE AND PYRIMIDINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 1999-12-29 | — | — | WO | disclosed |