SCHEMBL7756045

SCHEMBL7756045

CC(c1ccccc1)c1cc(O)c(C(C)c2ccccc2)cc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.71
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
ALOX15 P16050 3/20 0.42
CYP3A4 P08684 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
LMNA P02545 2/20 0.41
HKDC1 Q2TB90 1/20 0.41
ESR1 P03372 1/20 0.41
PDCD1 Q15116 1/20 0.41
ESR2 Q92731 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
KDM4E B2RXH2 3/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2C P18825 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26670161 0.93 TYR (0.69) TYRGABRA1GABRB2ALOX15CYP3A4
SCHEMBL9807308 0.90 TYR (0.61) TYRGABRA1GABRB2ALOX15CYP3A4
SCHEMBL9157459 0.89 TYR (0.74) TYRGABRA1GABRB2ALOX15CYP3A4
SCHEMBL11038220 0.88 TYR (0.62) TYRGABRA1GABRB2ALOX15CYP3A4
SCHEMBL8990374 0.86 TYR (0.61) TYRGABRA1GABRB2ALOX15CYP3A4
SCHEMBL14308079 0.86 TYR (0.56) TYRALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL7759216 0.86 TYR (0.56) TYRGABRA1GABRB2ALOX15CYP3A4
SCHEMBL11758511 0.86 TYR (0.56) TYRLMNAKDM4EALDH1A1MAPT
SCHEMBL14283825 0.86 TYR (0.56) TYRALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL9243488 0.84 TYR (0.58) TYRGABRA1GABRB2ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0320298-B1 Liquid-crystalline, thermotropic aromatic polyesters HIMONT ITALIA (IT) 1995-02-15 EP claimed
EP-0321107-B1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA (IT) 1995-01-25 EP claimed
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US claimed
US-5013819-A Units from aromatic or cycloaliphatic dicarboxy acid and from a mixture of mono-aralkyl substituted hydroquinones, matrix fo r composite material MONTEDISON S.P.A. (IT) 1991-05-07 US claimed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP claimed
US-4923947-A Thermotropic liquid crystalline aromatic polyesters of disubstituted 4,4'-dihydroxydiphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
US-4923955-A Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP claimed
EP-0321107-A1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-21 EP claimed
EP-0320298-A2 Liquid-crystalline, thermotropic aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-14 EP claimed
EP-0311389-A2 Thermotropic liquid-crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-04-12 EP claimed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
EP-0320298-A2 Liquid-crystalline, thermotropic aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-14 EP disclosed
EP-0311389-A2 Thermotropic liquid-crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-04-12 EP disclosed
EP-0300970-A1 Curable polyether amides CIBA-GEIGY AG (CH) 1989-01-25 EP disclosed
US-4764568-A SOLVENT INSOLUBLE CIBA-GEIGY CORPORATION (US) 1988-08-16 US disclosed
EP-0210136-A2 Curable polyether resins CIBA-GEIGY AG (CH) 1987-01-28 EP disclosed