SCHEMBL7756299

SCHEMBL7756299

CCCCCCCCCCC1=NCCN1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 4/20 0.56
NISCH Q9Y2I1 3/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
ADRA2B P18089 2/20 0.42
ADRA2C P18825 2/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
TAAR1 Q96RJ0 3/20 0.42
HTR1B P28222 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10491831 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
Hydrochloric Acid SCHEMBL9630422 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL5680179 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL2845525 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL107099 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL1626311 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL5675527 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL1736375 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL15561019 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B
SCHEMBL10621181 1.00 HTR1D (0.56) HTR1DNISCHMAOAMAOBADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4876249-A TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS THERAPEUTIC PATCH RESEARCH N.V. 1989-10-24 US claimed
EP-0296199-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA, Vithal J. (US) 1988-12-28 EP claimed
WO-1988004938-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA VITHAL J (US) 1988-07-14 WO claimed
EP-3118238-B1 LIQUID HARDENERS FOR CURING EPOXY RESINS (I) ALZCHEM TROSTBERG GMBH (DE) 2020-03-18 EP disclosed
EP-3118238-A1 LIQUID HARDENERS FOR CURING EPOXY RESINS (I) AlzChem AG (DE) 2017-01-18 EP disclosed
US-9499659-B2 Liquid hardeners for hardening epoxide resins (I) ALZCHEM AG (DE) 2016-11-22 US disclosed
EP-2880071-B1 LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (I) ALZCHEM AG (DE) 2016-09-07 EP disclosed
EP-2880072-B1 LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (II) ALZCHEM AG (DE) 2016-09-07 EP disclosed
US-9382374-B2 Liquid hardeners for hardening epoxide resins (II) ALZCHEM AG (DE) 2016-07-05 US disclosed
US-20150158972-A1 LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (I) ALZCHEM AG (DE) 2015-06-11 US disclosed
US-20150158970-A1 LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (II) ALZCHEM AG (DE) 2015-06-11 US disclosed
EP-0912465-B1 IMPROVED LITHIUM AND AMINE DISSOLVING METAL REDUCTION ALLERGAN SALES INC (US) 2001-04-04 EP disclosed
EP-0912465-A1 IMPROVED LITHIUM AND AMINE DISSOLVING METAL REDUCTION Allergan Sales, Inc. (US) 1999-05-06 EP disclosed
WO-1998003451-A1 IMPROVED LITHIUM AND AMINE DISSOLVING METAL REDUCTION ALLERGAN SALES, INC. (US) 1998-01-29 WO disclosed
US-5675038-A Lithium and amine dissolving metal reduction ALLERGAN (US) 1997-10-07 US disclosed
US-5076855-A METHOD OF THE CLEANING AGENT FOR CLEANING OF COMPRESSORS ESPECIALLY GAS TURBINES LANG & CO. CHEMISCH-TECHNISCHE PRODUKTE KOMMANDITGESELLSCHAFT (AT) 1991-12-31 US disclosed
EP-0460683-A2 Silicone mechanical emulsions for hair care DOW CORNING CORPORATION (US) 1991-12-11 EP disclosed
US-4876249-A TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS THERAPEUTIC PATCH RESEARCH N.V. 1989-10-24 US disclosed
EP-0296199-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA, Vithal J. (US) 1988-12-28 EP disclosed
WO-1988004938-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA VITHAL J (US) 1988-07-14 WO disclosed