Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722893 | 1.00 | CHRM2 (0.43) | CHRM2CHRM1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2634518 | 1.00 | CHRM2 (0.43) | CHRM2CHRM1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3960558 | 0.85 | MRGPRX4 (0.48) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL723430 | 0.85 | MRGPRX4 (0.48) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL19212480 | 0.85 | CHRM2 (0.40) | CHRM2CHRM1MAPTTSHR | |
| SCHEMBL19212482 | 0.85 | CHRM2 (0.40) | CHRM2CHRM1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL1354482 | 0.85 | MRGPRX4 (0.47) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| Hydrochloric Acid SCHEMBL723194 | 0.85 | MRGPRX4 (0.47) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL4659036 | 0.83 | CHRM2 (0.51) | CHRM2CHRM1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4660409 | 0.83 | CHRM2 (0.51) | CHRM2CHRM1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |