SCHEMBL7756537

SCHEMBL7756537

CCCCC[C@H]1CC[C@H](C2CCC(c3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
MAPT P10636 4/20 0.36
GAA P10253 2/20 0.36
CYP2C9 P11712 2/20 0.35
CYP1A2 P05177 3/20 0.33
MAPK1 P28482 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
SPHK1 Q9NYA1 3/20 0.33
CCR2 P41597 1/20 0.31
PKM P14618 1/20 0.31
NPC1 O15118 1/20 0.30
CYP2D6 P10635 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3437353 1.00 MEN1 (0.37) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL7756549 1.00 MEN1 (0.37) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL8734616 1.00 MEN1 (0.37) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL9764109 0.99 MAPT (0.38) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL9764498 0.99 MAPT (0.38) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL9763961 0.99 MAPT (0.38) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL9763852 0.99 MAPT (0.38) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL9763955 0.99 MAPT (0.38) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL9764345 0.99 MAPT (0.38) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL9763861 0.99 MAPT (0.38) MEN1KMT2AMAPTGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502407-B1 Nematic liquid-crystal composition for active matrix application SHARP KK (JP) 1996-02-07 EP claimed
EP-0718387-B1 A liquid crystal composition and a liquid crystal display element which contains it SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
EP-0833876-B1 NEMATIC LIQUID-CRYSTAL COMPOSITION MERCK PATENT GMBH (DE) 2000-09-13 EP disclosed
EP-0704512-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-03-08 EP disclosed
US-6004478-A LIQUID CRYSTAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-12-21 US disclosed
EP-0679707-B1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 1999-06-16 EP disclosed
EP-0672742-B1 A hexenediyne derivative and a liquid crystal composition CHISSO CORP (JP) 1999-02-10 EP disclosed
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed
EP-0833876-A1 NEMATIC LIQUID-CRYSTAL COMPOSITION MERCK PATENT GmbH (DE) 1998-04-08 EP disclosed
US-5730901-A Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-24 US disclosed
US-5389289-A Chemical and heat resistance MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-14 US disclosed
US-5330679-A Low temperature stability MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-07-19 US disclosed
EP-0597701-A1 Conjugated enyne derivative and liquid crystal composition CHISSO CORPORATION (JP) 1994-05-18 EP disclosed
US-5308543-A Fluorinated carbocyclic compounds; high voltage holding ratio; low temperature stability MERCK PATENT GESELLSCHAFT MIT BESRANKTER HAFTUNG (DE) 1994-05-03 US disclosed
EP-0502406-A1 Nematic liquid-crystal composition for active matrix application SHARP CORPORATION (JP) 1992-09-09 EP disclosed
EP-0502407-A1 Nematic liquid-crystal composition for active matrix application SHARP CORPORATION (JP) 1992-09-09 EP disclosed
EP-0471831-A1 LIQUID CRYSTALLINE MEDIUM. MERCK PATENT GMBH (DE) 1992-02-26 EP disclosed
WO-1991013947-A2 LIQUID CRYSTALLINE MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-09-19 WO disclosed
US-5032313-A Trifluorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1991-07-16 US disclosed
EP-0387032-A1 Trifluorobenzene derivatives and liquid crystal compositions containing the same Chisso Corporation (JP) 1990-09-12 EP disclosed