SCHEMBL7756837

SCHEMBL7756837

CN1C(C)(C)CC(OC(=O)Cl)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 3/20 0.35
HTT P42858 1/20 0.35
CYP2D6 P10635 1/20 0.35
HSD11B1 P28845 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ESR1 P03372 1/20 0.34
HSD17B10 Q99714 1/20 0.34
LMNA P02545 1/20 0.34
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
EPHX2 P34913 1/20 0.32
MEN1 O00255 1/20 0.31
SCN1A P35498 1/20 0.30
SCN2A Q99250 1/20 0.30
SCN3A Q9NY46 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9715125 0.98 HTT (0.37) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL9717169 0.86 TSHR (0.36) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL22127835 0.84 GAA (0.48) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL6714702 0.83 TSHR (0.37) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL5606458 0.83 TSHR (0.37) TSHRKMT2AGAAHTTCYP2D6
Hydrochloric Acid SCHEMBL9794751 0.83 GAA (0.35) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL25387445 0.82 TSHR (0.40) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL985161 0.82 TSHR (0.50) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL9397367 0.81 TSHR (0.34) TSHRKMT2AGAAHTTCYP2D6
SCHEMBL12360753 0.80 TSHR (0.36) TSHRKMT2AGAAHTTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2578620-B1 RESIN-ADDITIVE MASTERBATCH ADEKA CORP (JP) 2018-04-25 EP disclosed
EP-0850927-B1 Novel oxalic acid peroxide compositions and their uses ATOFINA CHEM INC (US) 2001-03-14 EP disclosed
US-5866712-A POLYMERIZATION AND CURING CATALYSTS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-02-02 US disclosed
EP-0850927-A1 Novel oxalic acid peroxide compositions and uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0472819-B1 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ATOCHEM NORTH AMERICA ELF (US) 1996-08-21 EP disclosed
US-5451654-A Addition polymerization catalyst ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-09-19 US disclosed
US-5387654-A Hydroxy-peroxides and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-02-07 US disclosed
EP-0381135-B1 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA (US) 1994-06-01 EP disclosed
US-5304649-A Curing agent for unsaturated polyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-19 US disclosed
EP-0233476-B1 PEROXIDE FREE RADICAL INITIATORS CONTAINING HINDERED AMINE LIGHT STABILIZER GROUPS ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1992-12-23 EP disclosed
EP-0472819-A2 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-04 EP disclosed
US-5039754-A Block copolymer;compatibilizing polymer blends and alloy ATOCHEM NORTH AMERICA, INC. (US) 1991-08-13 US disclosed
EP-0381135-A2 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA, INC. (US) 1990-08-08 EP disclosed
EP-0233476-A2 Peroxide free radical initiators containing hindered amine light stabilizer groups ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1987-08-26 EP disclosed
US-4525503-A POLYETHYLENE, POLYPROPYLENE CIBA-GEIGY S.P.A. (IT) 1985-06-25 US disclosed
US-4501837-A LIGHT, HEAT, AND OXIDATION STABILIZERS CIBA-GEIGY S.P.A. (IT) 1985-02-26 US disclosed
US-4369321-A Piperidine derivatives which are stabilizers for synthetic polymers CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1983-01-18 US disclosed