Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757075 | 1.00 | MAPT (0.37) | MAPTALDH1A1SMN1; SMN2CYP2C9MAOA | |
| SCHEMBL7754700 | 0.94 | CCR1 (0.36) | MAPTALDH1A1SMN1; SMN2CYP2C9MAOA | |
| SCHEMBL7754695 | 0.94 | CCR1 (0.36) | MAPTALDH1A1SMN1; SMN2CYP2C9MAOA | |
| SCHEMBL7751103 | 0.88 | TRPC3 (0.34) | MAPTALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL7751107 | 0.88 | TRPC3 (0.34) | MAPTALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL7757066 | 0.88 | KMT2A (0.40) | MAPTALDH1A1SMN1; SMN2CYP2C9DRD2 | |
| SCHEMBL7757062 | 0.88 | KMT2A (0.40) | MAPTALDH1A1SMN1; SMN2CYP2C9DRD2 | |
| SCHEMBL7757052 | 0.86 | CCR1 (0.35) | MAPTALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL7757056 | 0.86 | CCR1 (0.35) | MAPTALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL7754681 | 0.85 | KMT2A (0.44) | MAPTALDH1A1SMN1; SMN2CYP2C9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |