Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757090 | 1.00 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP1A2MAOA | |
| SCHEMBL10479748 | 0.98 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP1A2MAOA | |
| SCHEMBL10479746 | 0.98 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP1A2MAOA | |
| SCHEMBL8015260 | 0.96 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP1A2MAOA | |
| SCHEMBL8771408 | 0.96 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP1A2MAOA | |
| SCHEMBL8015254 | 0.96 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP1A2MAOA | |
| SCHEMBL8015266 | 0.96 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP1A2MAOA | |
| SCHEMBL7754624 | 0.95 | CYP3A4 (0.41) | SLC6A2SLC6A4SLC6A3MAOAMAOB | |
| SCHEMBL7510169 | 0.95 | CYP3A4 (0.41) | SLC6A2SLC6A4SLC6A3MAOAMAOB | |
| SCHEMBL8159218 | 0.94 | CYP3A4 (0.43) | SLC6A2SLC6A4SLC6A3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668285-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2001-05-02 | — | — | EP | disclosed |
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| US-5595686-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| US-5543539-A | TRANS CONFIGURATION DISPLAY ELEMENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0699683-A1 | Novel silacyclohexane compounds a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0668285-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-4917819-A | Cyclohexane derivative and liquid crystal composition containing same | CHISSO CORPORATION (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0205998-B1 | CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4797228-A | Cyclohexane derivative and liquid crystal composition containing same | CHISSO CORPORATION (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0205998-A1 | Cyclohexane derivative and liquid crystal composition containing same | Chisso Corporation (JP) | 1986-12-30 | — | — | EP | disclosed |