Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | LAP3 | P28838 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601220 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL27601208 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL27583707 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL28324323 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL15253464 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL27601200 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL9657415 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL5955504 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL28750757 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 | |
| SCHEMBL27583727 | 1.00 | TP53 (0.61) | TP53LAP3SPHK1OPRM1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482233-C | Compositions and methods for treating amyloidosis | UNIV KINGSTON (CH) | 2009-04-29 | — | — | CN | claimed |
| CN-1523992-A | Compositions and methods for treating amyloidosis | ʺ��ѧ | 2004-08-25 | — | — | CN | claimed |
| CN-115530172-B | Sterilization composition containing pyrimorph | 中国农业大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-101597196-B | Improved drug candidate and preparation method thereof | JIYAKETA CO., LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |
| WO-2015042020-A1 | STABLE CROSS-LINKED POLYMERS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2015-03-26 | — | — | WO | disclosed |
| WO-2015042028-A1 | HIGH TEMPERATURE STABLE CROSS-LINKED POLYMERS | THE LUBRIZOL CORPORATION (US) | 2015-03-26 | — | — | WO | disclosed |
| CN-101597196-A | Improved drug candidate and preparation method thereof | BELLUS HEALTH INTERNAT LTD (CH) | 2009-12-09 | — | — | CN | disclosed |
| CN-100528840-C | Improved drug candidates and methods for their preparation | NEUROCHEM INTERNAT LTD (CH) | 2009-08-19 | — | — | CN | disclosed |
| CN-100482233-C | Compositions and methods for treating amyloidosis | UNIV KINGSTON (CH) | 2009-04-29 | — | — | CN | disclosed |
| CN-1839117-A | Improved drug candidates and methods for their preparation | NEUROCHEM INTERNAT LTD (CH) | 2006-09-27 | — | — | CN | disclosed |
| CN-1523992-A | Compositions and methods for treating amyloidosis | ʺ��ѧ | 2004-08-25 | — | — | CN | disclosed |
| EP-0782131-B1 | Magnetic recording medium | TDK CORP (JP) | 2001-03-28 | — | — | EP | disclosed |
| EP-0782130-B1 | Magnetic recording medium | TDK CORP (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-6063500-A | MAGNETIC LAYER'S BINDER IS A BLEND OF A VINYL CHLORIDE COPOLYMER CONTAINING AMINE-MODIFIED VINYL UNITS AND ACIDIC GROUP-CONTAINING VINYL UNITS, AND POLYURETHANES HAVING SPECIFIC GLASS TRANSITION TEMPERATURES; RUNNING DURABILITY | TDK CORPORATION (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5935714-A | MAGNETIC LAYER COMPRISING MAGNETIC POWDER AND BINDER; BINDER COMPRISING MIXUTURE OF MODIFIED VINYL CHLORIDE COPOLYMER WITH AMINE AND ACIDIC FUNCTIONAL GROUPS AND POLYURETHANE RESIN; EXCELLENT RUNNING DURABILITY AND ELECTROMAGNETIC PROPERTIES | TDK CORPORATION (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0782130-A2 | Magnetic recording medium | TDK Corporation (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0782131-A2 | Magnetic recording medium | TDK Corporation (JP) | 1997-07-02 | — | — | EP | disclosed |