Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329470 | 1.00 | — | — | |
| SCHEMBL19172427 | 1.00 | KMT2A (0.56) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14856230 | 1.00 | KMT2A (0.56) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18595093 | 1.00 | KMT2A (0.56) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8564 | 1.00 | — | — | |
| SCHEMBL227313 | 1.00 | KMT2A (0.56) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| Iodide SCHEMBL28525407 | 0.97 | KMT2A (0.54) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5682894 | 0.97 | KMT2A (0.54) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| Iodide SCHEMBL28526462 | 0.97 | KMT2A (0.54) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| Bromide SCHEMBL28727067 | 0.97 | KMT2A (0.54) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001058496-A1 | SYSTEM FOR THE EXTRACORPOREAL TREATMENT OF BLOOD | ALLIED THERAPEUTICS LIMITED (GB) | 2001-08-16 | — | — | WO | claimed |