Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757638 | 0.85 | SMN1; SMN2 (0.33) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7757642 | 0.85 | SMN1; SMN2 (0.33) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7759888 | 0.85 | SMN1; SMN2 (0.35) | TNFMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7758798 | 0.85 | SMN1; SMN2 (0.35) | MEN1KMT2ATDP1SMN1; SMN2PDE3B | |
| SCHEMBL7756725 | 0.85 | SMN1; SMN2 (0.35) | TNFMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7758804 | 0.85 | SMN1; SMN2 (0.35) | MEN1KMT2ATDP1SMN1; SMN2PDE3B | |
| SCHEMBL7756730 | 0.85 | SMN1; SMN2 (0.35) | TNFMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7758886 | 0.84 | TNF (0.34) | TNFMEN1KMT2ATDP1ADORA3 | |
| SCHEMBL7758245 | 0.82 | MEN1 (0.38) | TNFMEN1KMT2ATDP1ADORA3 | |
| SCHEMBL7758868 | 0.81 | TNF (0.35) | TNFMEN1KMT2ATDP1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |