SCHEMBL7757733

SCHEMBL7757733

CCC[Si@H]1CC[C@H](C2CCC(c3cc(F)c(OCC(F)F)c(F)c3)CC2)CC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8448502 1.00 MAPT (0.31) MAPTKMT2ANPSR1
SCHEMBL7757742 1.00 MAPT (0.31) MAPTKMT2ANPSR1
SCHEMBL7757738 1.00 MAPT (0.31) MAPTKMT2ANPSR1
SCHEMBL7756499 0.93
SCHEMBL8455862 0.93
SCHEMBL7756515 0.93
SCHEMBL7756509 0.93
SCHEMBL7757263 0.92
SCHEMBL7757260 0.92
SCHEMBL8449059 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718387-B1 A liquid crystal composition and a liquid crystal display element which contains it SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
US-6004478-A LIQUID CRYSTAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-12-21 US disclosed
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed
EP-0732335-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-09-18 EP disclosed
EP-0718387-A1 A liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-26 EP disclosed