Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344699 | 0.86 | — | — | |
| SCHEMBL466022 | 0.79 | TSHR (0.36) | TSHRALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL11184033 | 0.77 | — | — | |
| SCHEMBL59249 | 0.77 | — | — | |
| SCHEMBL3481982 | 0.76 | — | — | |
| SCHEMBL15828888 | 0.76 | — | — | |
| SCHEMBL19356850 | 0.75 | TSHR (0.39) | TSHRALDH1A1DNM1OPRM1 | |
| SCHEMBL18030152 | 0.74 | TSHR (0.33) | TSHRALDH1A1SMN1; SMN2DNM1OPRM1 | |
| SCHEMBL10592014 | 0.74 | TSHR (0.36) | TSHRALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL892183 | 0.73 | TSHR (0.37) | TSHRALDH1A1DNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258913-B1 | ADDITION-POLYSILOXANE COPOLYMERS | WACKER-CHEMIE GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-0953004-B1 | POLYMERIC ORGANOSILICON COMPOUNDS, THEIR PRODUCTION AND USE | WACKER CHEMIE GMBH (DE) | 2001-04-04 | — | — | EP | disclosed |
| EP-0953004-A1 | POLYMERIC ORGANOSILICON COMPOUNDS, THEIR PRODUCTION AND USE | Wacker-Chemie GmbH (DE) | 1999-11-03 | — | — | EP | disclosed |
| WO-1998031727-A1 | POLYMERIC ORGANOSILICON COMPOUNDS, THEIR PRODUCTION AND USE | WACKER-CHEMIE GMBH (DE) | 1998-07-23 | — | — | WO | disclosed |