Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118335 | 0.89 | MEN1 (0.49) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1248421 | 0.82 | CCNA2 (0.49) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1250063 | 0.74 | MAPT (0.44) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1249747 | 0.74 | MAPT (0.46) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7757594 | 0.73 | MAPT (0.45) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7757019 | 0.73 | MAPT (0.48) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1248186 | 0.72 | MAPT (0.45) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1250757 | 0.72 | MAPT (0.52) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1250520 | 0.71 | MAPT (0.45) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1250879 | 0.71 | CDK5 (0.54) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056567-A1 | 2,4-DIAMINOTHIAZOLE DERIVATIVES AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 (GSK-3) INHIBITORS | NOVO NORDISK A/S (DK) | 2001-08-09 | — | — | WO | disclosed |