Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290602 | 0.92 | SMN1; SMN2 (0.41) | SMN1; SMN2CPT2ACLYTDP1CYP2D6 | |
| Hydrochloric Acid SCHEMBL11284194 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2CPT2ACLYTDP1CYP2D6 | |
| Dimethylamine SCHEMBL9055579 | 0.83 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL653302 | 0.83 | CYP2C19 (0.37) | TP53CPT2ACLYCYP2D6TSHR | |
| SCHEMBL290603 | 0.81 | CPT2 (0.32) | SMN1; SMN2CPT2ACLY | |
| Ammonia Solution, Strong SCHEMBL5048410 | 0.81 | CYP2D6 (0.35) | TP53CPT2ACLYCYP2D6TSHR | |
| SCHEMBL20521418 | 0.81 | CYP2D6 (0.35) | TP53CPT2ACLYCYP2D6TSHR | |
| SCHEMBL28564581 | 0.81 | CYP2D6 (0.35) | TP53CPT2ACLYCYP2D6TSHR | |
| SCHEMBL9387459 | 0.81 | CYP2D6 (0.35) | TP53CPT2ACLYCYP2D6TSHR | |
| SCHEMBL2971627 | 0.81 | CYP2D6 (0.35) | TP53CPT2ACLYCYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717074-B | Composition comprising isosorbide monoester and alcohol comprising at least one aromatic group | 克拉里安特国际有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-105744928-A | Use of an edelweiss extract in hair care for the prevention of hair graying | 帝斯曼知识产权资产管理有限公司 | 2016-07-06 | — | — | CN | disclosed |
| WO-2001064043-A1 | PERSIMMON VINEGAR POWDER AND PROCESS FOR PREPARING THE SAME | BONGLIM CO, LTD (KR) | 2001-09-07 | — | — | WO | disclosed |