Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063625 | 0.89 | CYP1A2 (0.51) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL8947821 | 0.88 | MEN1 (0.61) | GAACHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL20595548 | 0.86 | CHRM2 (0.70) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL8947879 | 0.86 | CPT1B (0.53) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL30279513 | 0.85 | MEN1 (0.59) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL8063657 | 0.85 | CYP2C19 (0.56) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL5559041 | 0.85 | MEN1 (0.59) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL8058972 | 0.84 | CHRM2 (0.76) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL8061146 | 0.84 | CPT1B (0.52) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL8048454 | 0.84 | CPT1B (0.52) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617027-B1 | N-Benzylpiperazinderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-06-07 | — | — | EP | claimed |
| US-5492913-A | TREATING NEURONAL DISORDERS RESULTING FROM DYSFUNCTION OF OXIDATIVE METABOLISM | ADIR ET COMPAGNIE (FR) | 1996-02-20 | — | — | US | claimed |
| JP-7002814-A | — | — | None | — | — | JP | disclosed |
| EP-0847999-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |
| US-5849745-A | N-benzylpiperazine compounds | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| EP-0847999-A1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-06-17 | — | — | EP | disclosed |
| US-5492913-A | TREATING NEURONAL DISORDERS RESULTING FROM DYSFUNCTION OF OXIDATIVE METABOLISM | ADIR ET COMPAGNIE (FR) | 1996-02-20 | — | — | US | disclosed |
| JP-H072814-A | NEW N-BENZYLPIPERAZINE COMPOUND AND ITS PREPARATION | ADIR | 1995-01-06 | — | — | JP | disclosed |