Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ANXA2 | P07355 | 2/20 | 0.35 |
| ▸ | S100A10 | P60903 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758872 | 1.00 | TSHR (0.38) | TSHRLMNAKMT2AKDM4EMAPT | |
| SCHEMBL7757674 | 0.86 | KMT2A (0.36) | LMNAKMT2AKDM4EMAPTHTT | |
| SCHEMBL7757666 | 0.86 | KMT2A (0.36) | LMNAKMT2AKDM4EMAPTHTT | |
| SCHEMBL7758261 | 0.86 | KMT2A (0.36) | LMNAKMT2AKDM4EMAPTHTT | |
| SCHEMBL7757631 | 0.85 | KMT2A (0.35) | TSHRLMNAKMT2AKDM4EMAPT | |
| SCHEMBL7757628 | 0.85 | KMT2A (0.35) | TSHRLMNAKMT2AKDM4EMAPT | |
| SCHEMBL12752298 | 0.85 | KMT2A (0.35) | TSHRLMNAKMT2AKDM4EMAPT | |
| SCHEMBL7756567 | 0.84 | KMT2A (0.37) | KMT2AMAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL7753955 | 0.84 | KMT2A (0.35) | KMT2AMEN1 | |
| SCHEMBL7753958 | 0.84 | KMT2A (0.35) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |