Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639836 | 0.83 | CYP1A2 (0.54) | CYP1A2CYSLTR1CYSLTR2GPBAR1MEN1 | |
| Hydrochloric Acid SCHEMBL3498851 | 0.81 | CYP1A2 (0.53) | CYP1A2CYSLTR1CYSLTR2GPBAR1MEN1 | |
| SCHEMBL140815 | 0.81 | CYP1A2 (0.65) | CYP1A2CYSLTR1CYSLTR2GPBAR1MGAM | |
| SCHEMBL728064 | 0.79 | CYP1A2 (0.54) | CYP1A2CYSLTR1CYSLTR2MEN1GAA | |
| SCHEMBL11641036 | 0.79 | CYP1A2 (0.54) | CYP1A2CYSLTR1CYSLTR2MEN1GAA | |
| SCHEMBL14805320 | 0.78 | CYP1A2 (0.67) | CYP1A2CYSLTR1CYSLTR2GPBAR1MGAM | |
| SCHEMBL9480225 | 0.78 | CYP1A2 (0.62) | CYP1A2CYSLTR1CYSLTR2MEN1GAA | |
| SCHEMBL1163526 | 0.78 | CYP1A2 (0.57) | CYP1A2CYSLTR1CYSLTR2GPBAR1MEN1 | |
| SCHEMBL28635312 | 0.78 | CYP1A2 (0.61) | CYP1A2CYSLTR1CYSLTR2GPBAR1MGAM | |
| SCHEMBL29775305 | 0.78 | CYP1A2 (0.53) | CYP1A2CYSLTR1CYSLTR2GPBAR1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7002781-A | — | — | None | — | — | JP | disclosed |
| US-6207833-B1 | REACTING 2-CHLOROQUINOLINE WITH MERCAPTOACETIC ACID | LOBA FEINCHEMIE AG (AU) | 2001-03-27 | — | — | US | disclosed |
| JP-2001031653-A | PRODUCTION OF 2-QUINOLINYLTHIOACETIC ACID OR ITS HYDROCHLORIDE | LOBA FEINCHEMIE AG | 2001-02-06 | — | — | JP | disclosed |
| EP-1063233-A1 | Process for the preparation of 2-quinolinylthio-acetic acid and its hydrochloride | LOBA FEINCHEMIE AKTIENGESELLSCHAFT (AT) | 2000-12-27 | — | — | EP | disclosed |
| EP-1063233-A1 | Process for the preparation of 2-quinolinylthio-acetic acid and its hydrochloride | LOBA FEINCHEMIE AKTIENGESELLSCHAFT (AT) | 2000-12-27 | — | — | EP | disclosed |
| EP-0631176-B1 | Photothermographic materials | EASTMAN KODAK CO (US) | 2000-12-13 | — | — | EP | disclosed |
| US-5594143-A | IMAGE STABILIZERS, ANTIFOGGING AGENTS | IMATION CORP. (US) | 1997-01-14 | — | — | US | disclosed |
| US-5460938-A | Containing a halogenated, sulfone-containing quinoline compound as antifogging agent | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| JP-H072781-A | PHOTOTHERMOGRAPHIC MATERIAL | MINNESOTA MINING & MFG CO <3M> | 1995-01-06 | — | — | JP | disclosed |
| EP-0631176-A1 | Photothermographic materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |