Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590448 | 0.95 | TSHR (0.45) | TSHRPOLBMAPK1TP53GAA | |
| SCHEMBL27569243 | 0.90 | CA1 (0.35) | TSHRPOLBMAPK1TP53GAA | |
| SCHEMBL3784428 | 0.76 | CYP3A4 (0.39) | TSHRMAPK1TP53GAARECQL | |
| SCHEMBL7077319 | 0.73 | TP53 (0.42) | TP53CYP3A4ALDH1A1 | |
| SCHEMBL11051483 | 0.73 | TSHR (0.39) | TSHRPOLBMAPK1TP53GAA | |
| SCHEMBL10476964 | 0.72 | TSHR (0.34) | TSHRPOLBMAPK1TP53GAA | |
| SCHEMBL28405609 | 0.72 | MEN1 (0.33) | POLBGAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL472107 | 0.71 | TSHR (0.59) | TSHRPOLBMAPK1TP53GAA | |
| SCHEMBL3780920 | 0.71 | TSHR (0.46) | TSHRPOLBMAPK1TP53GAA | |
| SCHEMBL472066 | 0.69 | CYP3A4 (0.33) | TSHRTP53GAARECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593877-B1 | Composition for optical material | SHOWA DENKO KK (JP) | 1999-01-27 | — | — | EP | claimed |
| US-5380809-A | Composition for optical material | SHOWA DENKO K.K. (JP) | 1995-01-10 | — | — | US | claimed |
| EP-0593877-A1 | Composition for optical material | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-04-27 | — | — | EP | claimed |
| CN-1301354-A | Resin composition for plastic lens use and plastic lens | SHOWA DENKO KK (JP) | 2001-06-27 | — | — | CN | disclosed |
| EP-1085350-A1 | RESIN COMPOSITION FOR PLASTIC LENS USE AND PLASTIC LENS | Showa Denko Kabushiki Kaisha (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0593877-B1 | Composition for optical material | SHOWA DENKO KK (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-5380809-A | Composition for optical material | SHOWA DENKO K.K. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0593877-A1 | Composition for optical material | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-04-27 | — | — | EP | disclosed |