Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498314 | 0.94 | ACE (0.37) | GBA1BCHEACEALDH1A1SMN1; SMN2 | |
| SCHEMBL474124 | 0.89 | GBA1 (0.42) | GBA1CYP1A2BCHEACES1PR1 | |
| SCHEMBL8602272 | 0.89 | GBA1 (0.45) | GBA1CYP1A2BCHEALDH1A1CHRNB2 | |
| SCHEMBL11775340 | 0.89 | GBA1 (0.45) | GBA1CYP1A2BCHEALDH1A1CHRNB2 | |
| SCHEMBL3270939 | 0.89 | GBA1 (0.45) | GBA1CYP1A2BCHEALDH1A1CHRNB2 | |
| SCHEMBL6130819 | 0.89 | GBA1 (0.45) | GBA1CYP1A2BCHEALDH1A1CHRNB2 | |
| SCHEMBL6535779 | 0.89 | GBA1 (0.45) | GBA1CYP1A2BCHEALDH1A1CHRNB2 | |
| SCHEMBL3957901 | 0.89 | CYP1A2 (0.39) | GBA1CYP1A2BCHEACES1PR1 | |
| SCHEMBL9474303 | 0.89 | GBA1 (0.45) | GBA1CYP1A2BCHEALDH1A1CHRNB2 | |
| SCHEMBL9568882 | 0.87 | GBA1 (0.43) | GBA1CYP1A2BCHEACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090301-A1 | NON-INVASIVE TRANSDERMAL DETECTION OF ANALYTES | Transderm Diagnostics, Inc. (US) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067645-A9 | NON-INVASIVE TRANSDERMAL DETECTION OF ANALYTES | TRANSDERM DIAGNOSTICS INC (US) | 2000-03-16 | — | — | WO | claimed |
| WO-1999067645-A1 | NON-INVASIVE TRANSDERMAL DETECTION OF ANALYTES | TRANSDERM DIAGNOSTICS, INC. (US) | 1999-12-29 | — | — | WO | claimed |