Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016818 | 1.00 | CYP2C9 (0.38) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL9008545 | 1.00 | CYP2C9 (0.38) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7759580 | 1.00 | CYP2C9 (0.38) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7761176 | 0.96 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7761177 | 0.96 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8415908 | 0.96 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7752952 | 0.90 | SPHK1 (0.38) | SPHK1PTGS1PTGS2SPHK2 | |
| SCHEMBL7752954 | 0.90 | SPHK1 (0.38) | SPHK1PTGS1PTGS2SPHK2 | |
| SCHEMBL8416864 | 0.89 | SPHK1 (0.35) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8416863 | 0.89 | SPHK1 (0.35) | CYP2C9MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0711777-A1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |