SCHEMBL7759970

SCHEMBL7759970

CCC(=O)O[SiH2]c1ccccc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
KCNQ2 O43526 1/20 0.41
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 5/20 0.39
SOAT1 P35610 2/20 0.38
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
ELANE P08246 1/20 0.37
HTT P42858 2/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29026463 0.75 ELANE (0.43) MAPTALDH1A1SMN1; SMN2KDM4EL3MBTL1
SCHEMBL27593447 0.74 SMN1; SMN2 (0.40) MAPTKCNQ2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL2058257 0.71 KDM4E (0.53) MAPTALDH1A1SMN1; SMN2KDM4EL3MBTL1
Biphenyl SCHEMBL27773340 0.71 MAPT (0.53) MAPTALDH1A1SMN1; SMN2KDM4EL3MBTL1
Propionic Acid SCHEMBL29662033 0.70 MAPT (0.52) MAPTKCNQ2ALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL28754662 0.70 SCN1A (0.60) ALDH1A1SMN1; SMN2KDM4EL3MBTL1SCN1A
SCHEMBL28321273 0.70 KDM4E (0.48) MAPTALDH1A1SMN1; SMN2KDM4EL3MBTL1
SCHEMBL8400324 0.69 KMT2A (0.49) SCN1ASCN2ASCN3AKMT2A
SCHEMBL28457188 0.68 MAPT (0.50) MAPTALDH1A1SMN1; SMN2L3MBTL1HTT
Biphenyl SCHEMBL11806686 0.67 SMN1; SMN2 (0.53) MAPTALDH1A1SMN1; SMN2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed