Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099722 | 0.79 | TDP1 (0.47) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL9283778 | 0.76 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL11213886 | 0.76 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL1289265 | 0.76 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL7191532 | 0.76 | TDP1 (0.45) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL13908443 | 0.75 | TDP1 (0.43) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL25644470 | 0.74 | TDP1 (0.40) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL9312658 | 0.74 | — | — | |
| SCHEMBL464886 | 0.74 | — | — | |
| SCHEMBL1162425 | 0.74 | SMN1; SMN2 (0.38) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786464-B1 | A method for manufacturing acryloxypropylsilane | CHISSO CORP (JP) | 2001-05-30 | — | — | EP | disclosed |
| US-5750753-A | CATALYTIC HYDROSILATION WITH PHOSPHORUS PROMOTER | CHISSO CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0786464-A1 | A method for manufacturing acryloxypropylsilane | Chisso Corporation (JP) | 1997-07-30 | — | — | EP | disclosed |