SCHEMBL7762090

SCHEMBL7762090

CCCCCCC[SiH]1CCC(COc2cc(F)c(OC(F)F)c(F)c2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.31
PARP15 Q460N3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762094 1.00 PARP10 (0.31) PARP10PARP15
SCHEMBL7761624 0.87 PARP10 (0.31) PARP10PARP15
SCHEMBL7761626 0.87 PARP10 (0.31) PARP10PARP15
SCHEMBL7760411 0.86 PARP10 (0.34) PARP10PARP15
SCHEMBL7760416 0.86 PARP10 (0.34) PARP10PARP15
SCHEMBL7763780 0.84 PDE4A (0.32) PARP10PARP15
SCHEMBL7763777 0.84 PDE4A (0.32) PARP10PARP15
SCHEMBL7763784 0.84 PDE4A (0.32) PARP10PARP15
SCHEMBL7762433 0.83
SCHEMBL7762430 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714899-B1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHINETSU CHEMICAL CO (JP) 2001-04-18 EP disclosed
EP-0714899-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-05 EP disclosed