SCHEMBL776231

SCHEMBL776231

[CH]=CC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6485151 0.70
SCHEMBL714788 0.70
SCHEMBL1885055 0.67
SCHEMBL477935 0.59
SCHEMBL14890985 0.59
SCHEMBL346587 0.59
SCHEMBL1959816 0.59
SCHEMBL7602141 0.56
SCHEMBL10011816 0.56
SCHEMBL1006007 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4373825-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2024-05-29 EP claimed
WO-2023137297-A2 5,6-DIHYDRO-4H-THIENO[2,3-C]PYRROLE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2023-07-20 WO claimed
WO-2023004376-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2023-01-26 WO claimed
US-20050209251-A1 Substituted pyrazolo-pyrimidine-4-ones BAYER CROPSCIENCE AG (DE) 2005-09-22 US claimed
EP-4373825-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2024-05-29 EP disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
WO-2024104455-A1 CDK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 山东绿叶制药有限公司 2024-05-23 WO disclosed
CN-118047801-A KRAS inhibitor compound, pharmaceutical composition and application thereof 广东东阳光药业股份有限公司 2024-05-17 CN disclosed
WO-2024086194-A1 COMBINATION THERAPY FOR TREATMENT OF CANCER Suvalent Therapeutics, Inc. (US) 2024-04-25 WO disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-3808738-B1 PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2024-04-17 EP disclosed
CN-117886759-A Method for directly functionalizing alpha-trifluoromethyl olefin C (sp 3) -F 南昌航空大学 2024-04-16 CN disclosed
EP-0679707-A1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1995-11-02 EP disclosed
US-5104440-A Herbicides CIBA-GEIGY CORPORATION (US) 1992-04-14 US disclosed
US-5041603-A Pre-, postemergence herbicides, plant growth regulators, chemical intermediates CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
EP-0248245-B1 2-FLUOROALKENYL-PHENYL-SULFONIC-ACID DERIVATIVES CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-4780125-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1988-10-25 US disclosed
EP-0102925-B1 N-PHENYLSULFONYL-N'-PYRIMIDINYL- AND -TRIAZINYL UREA CIBA-GEIGY AG (CH) 1988-10-12 EP disclosed
EP-0248245-A2 2-Fluoroalkenyl-phenyl-sulfonic-acid derivatives CIBA-GEIGY AG (CH) 1987-12-09 EP disclosed
EP-0102925-A2 N-phenylsulfonyl-N'-pyrimidinyl- and -triazinyl urea CIBA-GEIGY AG (CH) 1984-03-14 EP disclosed