SCHEMBL7763539

SCHEMBL7763539

FC(=C(Cl)C(F)(F)F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636783 0.73
SCHEMBL7636776 0.73
SCHEMBL668431 0.69
SCHEMBL20679246 0.69
SCHEMBL668432 0.69
SCHEMBL2321646 0.69
SCHEMBL333187 0.69
SCHEMBL1999538 0.69
SCHEMBL333188 0.69
SCHEMBL249362 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436759-B Gas phase preparation method of 1,2, 4-heptafluoro-2-butene 浙江省化工研究院有限公司 2023-10-27 CN claimed
CN-110950735-B Method for preparing 1,1,1,4,4, 4-hexafluoro-2-butyne by gas phase method 浙江巨化技术中心有限公司 2022-08-30 CN claimed
CN-110950735-A Method for preparing 1,1,1,4,4, 4-hexafluoro-2-butyne by gas phase method 浙江巨化技术中心有限公司 2020-04-03 CN claimed
CN-113677650-B Process for preparing Z-1, 4-hexafluorobut-2-ene and intermediates for preparing the same 科慕埃弗西有限公司 2024-04-12 CN disclosed
CN-114436759-B Gas phase preparation method of 1,2, 4-heptafluoro-2-butene 浙江省化工研究院有限公司 2023-10-27 CN disclosed
CN-111018657-B Integrated method for preparing Z-1,1,1,4,4,4-hexafluoro-2-butene 科慕埃弗西有限公司 2023-03-10 CN disclosed
CN-110950735-B Method for preparing 1,1,1,4,4, 4-hexafluoro-2-butyne by gas phase method 浙江巨化技术中心有限公司 2022-08-30 CN disclosed
CN-110950735-B Method for preparing 1,1,1,4,4, 4-hexafluoro-2-butyne by gas phase method 浙江巨化技术中心有限公司 2022-08-30 CN disclosed
EP-3947327-A1 PROCESSES FOR PRODUCING Z-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE AND INTERMEDIATES FOR PRODUCING SAME The Chemours Company FC, LLC (US) 2022-02-09 EP disclosed
WO-2020206322-A1 PROCESSES FOR PRODUCING Z-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE AND INTERMEDIATES FOR PRODUCING SAME THE CHEMOURS COMPANY FC, LLC (US) 2020-10-08 WO disclosed
CN-110950735-A Method for preparing 1,1,1,4,4, 4-hexafluoro-2-butyne by gas phase method 浙江巨化技术中心有限公司 2020-04-03 CN disclosed
CN-110950735-A Method for preparing 1,1,1,4,4, 4-hexafluoro-2-butyne by gas phase method 浙江巨化技术中心有限公司 2020-04-03 CN disclosed
US-6245319-B1 Colloidal dispersions of perfluoropentane SONUS PHARMACEUTICALS, INC. 2001-06-12 US disclosed
EP-0680341-B1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMA INC (US) 2001-05-09 EP disclosed
EP-0680341-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1995-11-08 EP disclosed
WO-1995004038-A1 SUBSTITUTED 2-ARYL-TRIFLUOROMETHYLPYRROLES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1995-02-09 WO disclosed
WO-1994016739-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1994-08-04 WO disclosed