Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 4/20 | 0.58 |
| ▸ | PIM1 | P11309 | 3/20 | 0.58 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.58 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.58 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.58 |
| ▸ | MARK3 | P27448 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | CLK2 | P49760 | 1/20 | 0.58 |
| ▸ | ITK | Q08881 | 1/20 | 0.58 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.58 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762870 | 0.95 | AURKB (0.53) | AURKBPIM1PIM3CLK4MAP4K4 | |
| Hydrochloric Acid SCHEMBL6586250 | 0.95 | AURKB (0.52) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6582905 | 0.88 | MAP4K4 (0.75) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6806294 | 0.87 | AURKB (0.77) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6591203 | 0.86 | PIM1 (0.54) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6583962 | 0.84 | PIM1 (0.53) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6581364 | 0.84 | MAP4K4 (0.62) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6591082 | 0.84 | AURKB (0.50) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6590773 | 0.83 | AURKB (0.43) | AURKBPIM1PIM3CLK4MAP4K4 | |
| SCHEMBL6579002 | 0.83 | MAP4K4 (0.68) | AURKBPIM1PIM3CLK4MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |