SCHEMBL7764141

SCHEMBL7764141

C=CCN(C)CCCCCCOc1ccc(-c2ccc(Br)cc2)c(F)c1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LSS P48449 20/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3691954 0.83 LSS (0.68) LSSMEN1KMT2A
SCHEMBL7684557 0.81 LSS (0.80) LSSMEN1KMT2A
SCHEMBL21114072 0.81 LSS (0.63) LSSMEN1KMT2A
SCHEMBL21122124 0.81 LSS (0.62) LSSMEN1KMT2A
SCHEMBL3674881 0.81 LSS (1.00) LSSMEN1KMT2A
SCHEMBL30583394 0.81 LSS (1.00) LSS
SCHEMBL8762340 0.81 LSS (1.00) LSS
SCHEMBL8762503 0.81 LSS (0.73) LSS
SCHEMBL4309736 0.81 LSS (1.00) LSS
Bromide SCHEMBL7685880 0.80 LSS (0.98) LSSMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778264-B1 Tertiary amines having antimycotic and cholesterol lowering activity HOFFMANN LA ROCHE (CH) 2001-07-11 EP claimed