Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | NPY4R | P50391 | 2/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29476474 | 0.93 | C3AR1 (0.45) | C3AR1NOD1GNPATSLC15A2EPHX2 | |
| SCHEMBL187696 | 0.93 | C3AR1 (0.45) | C3AR1NOD1GNPATSLC15A2EPHX2 | |
| SCHEMBL2116832 | 0.93 | C3AR1 (0.45) | C3AR1NOD1GNPATSLC15A2EPHX2 | |
| SCHEMBL4587702 | 0.92 | C3AR1 (0.44) | C3AR1NOD1GNPATSLC15A2EPHX2 | |
| SCHEMBL2815688 | 0.92 | C3AR1 (0.44) | C3AR1NOD1GNPATSLC15A2EPHX2 | |
| Benzene SCHEMBL6278673 | 0.90 | C3AR1 (0.49) | C3AR1NOD1GNPATSLC15A2EPHX2 | |
| SCHEMBL29875467 | 0.88 | SLC15A2 (0.44) | C3AR1NOD1GNPATSLC15A2NPY4R | |
| SCHEMBL3952951 | 0.88 | SLC15A2 (0.44) | C3AR1NOD1GNPATSLC15A2NPY4R | |
| SCHEMBL29875780 | 0.88 | SLC15A2 (0.44) | C3AR1NOD1GNPATSLC15A2NPY4R | |
| SCHEMBL3952924 | 0.88 | SLC15A2 (0.44) | C3AR1NOD1GNPATSLC15A2NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105475-A1 | TISSUE FACTOR PROTEIN VARIANTS WITH INCREASED AFFINITY FOR COAGULATION FACTOR FVII/FVIIA | Genentech, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000004148-A1 | TISSUE FACTOR PROTEIN VARIANTS WITH INCREASED AFFINITY FOR COAGULATION FACTOR FVII/FVIIA | GENENTECH, INC. (US) | 2000-01-27 | — | — | WO | disclosed |