SCHEMBL7764689

SCHEMBL7764689

O=[C]CCN1CCC(Cc2ccccc2)CC1

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 3/20 0.67
CARM1 Q86X55 2/20 0.65
PRMT6 Q96LA8 2/20 0.65
PRMT3 O60678 1/20 0.65
PRMT1 Q99873 1/20 0.65
PRMT8 Q9NR22 1/20 0.65
SIGMAR1 Q99720 1/20 0.61
GRIN2B Q13224 2/20 0.60
KCNH2 Q12809 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7238621 0.84 CCR3 (0.67) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL5888850 0.84 CCR3 (0.67) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL10772998 0.84 CCR3 (0.65) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL6976178 0.81 GRIN2B (0.83) GRIN2B
SCHEMBL7403790 0.80 CCR3 (1.00) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL7403436 0.80 CCR3 (0.75) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL95597 0.79 CCR3 (0.73) CCR3CARM1PRMT6PRMT3PRMT1
Hydrochloric Acid SCHEMBL7026911 0.79 CCR3 (0.73) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL21386112 0.79 CCR3 (0.73) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL360084 0.79 KCNH2 (0.77) CCR3CARM1PRMT6PRMT3PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107983-A2 BENZODIAZEPINE AND BENZOTHIAZEPINE DERIVATIVES AND HBSAG PEPTIDES BINDING TO ANNEXINS, THEIR COMPOSITIONS AND USE INNOGENETICS N.V. (BE) 2001-06-20 EP disclosed
WO-2000012547-A2 BENZODIAZEPINES AND BENZOTHIAZEPINES DERIVATIVES AND HBSAG PEPTIDES BINDING TO ANNEXINS, THEIR COMPOSITIONS AND USE INNOGENETICS N.V. (BE) 2000-03-09 WO disclosed