⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769055 | 0.97 | — | — | |
| SCHEMBL15161773 | 0.90 | — | — | |
| SCHEMBL4201260 | 0.82 | — | — | |
| SCHEMBL197056 | 0.75 | NR1H2 (0.31) | — | |
| SCHEMBL5465892 | 0.75 | NR1H2 (0.31) | — | |
| SCHEMBL9516922 | 0.75 | NR1H2 (0.31) | — | |
| SCHEMBL940553 | 0.75 | NR1H2 (0.31) | — | |
| SCHEMBL202812 | 0.75 | NR1H2 (0.31) | — | |
| SCHEMBL5473432 | 0.75 | NR1H2 (0.31) | — | |
| SCHEMBL5463725 | 0.75 | NR1H2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114824-B1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6284907-B1 | REACTING HYDROGEN HALIDE WITH THE CORRESPONDING 1,3-DIHYDRO-1,1,3,3-TETRA(ORGANYL)DISILOXANES; CATALYST SELECTED FROM TRANSITION METALS OF THE 8TH SUBGROUP OF THE PERIODIC TABLE OF THE ELEMENTS, OR COMPOUNDS OR COMPLEXES | WACKER-CHEMIE GMBH (DE) | 2001-09-04 | — | — | US | disclosed |
| EP-1114824-A1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | Wacker-Chemie GmbH (DE) | 2001-07-11 | — | — | EP | disclosed |
| EP-1110965-A2 | Process for preparing 1,3-dihalo-1,1,3,3-tetra(organyl)disiloxanes | Wacker-Chemie GmbH (DE) | 2001-06-27 | — | — | EP | disclosed |