⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19927519 | 0.90 | — | — | |
| SCHEMBL7768613 | 0.86 | — | — | |
| SCHEMBL7768610 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL9277808 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL2136101 | 0.78 | — | — | |
| SCHEMBL3481640 | 0.78 | — | — | |
| SCHEMBL3482412 | 0.75 | — | — | |
| SCHEMBL21112911 | 0.75 | — | — | |
| SCHEMBL19926952 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL3481899 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784718-B1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYETHERPOLYSILOXANE BLOCK COPOLYMERS | HENKEL AG & CO KGAA (DE) | 2024-06-26 | — | — | EP | disclosed |
| CN-114096590-B | UV and/or thermally curable silicone-based materials and formulations | 汉高股份有限及两合公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11807758-B2 | Siloxane polymer and method of producing siloxane polymer | JNC CORPORATION (JP) | 2023-11-07 | — | — | US | disclosed |
| US-20220411634-A1 | SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY | HENKEL AG & CO. KGAA (DE) | 2022-12-29 | — | — | US | disclosed |
| EP-4108726-A1 | SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY | Henkel AG & Co. KGaA (DE) | 2022-12-28 | — | — | EP | disclosed |
| US-11326027-B2 | Process for the preparation of hydroxyl-functionalized polysiloxanes | HENKEL AG & CO. KGAA (DE) | 2022-05-10 | — | — | US | disclosed |
| CN-114096590-A | UV and/or thermally curable silicone-based materials and formulations | 汉高知识产权控股有限责任公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-3953412-A1 | UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS | Henkel IP & Holding GmbH (DE) | 2022-02-16 | — | — | EP | disclosed |
| US-20220025180-A1 | UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS | HENKEL AG & CO. KGAA (DE) | 2022-01-27 | — | — | US | disclosed |
| US-20210238419-A1 | SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER | JNC CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
| EP-3336129-B1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYSILOXANES | HENKEL AG & CO KGAA (DE) | 2021-03-17 | — | — | EP | disclosed |
| US-20210040269-A1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYETHER-POLYSILOXANE BLOCK COPOLYMERS | HENKEL AG & CO KGAA (DE) | 2021-02-11 | — | — | US | disclosed |
| CN-112004862-A | Process for preparing hydroxy-functionalized polyether-polysiloxane block copolymers | 汉高股份有限及两合公司 | 2020-11-27 | — | — | CN | disclosed |
| US-20190322808-A1 | Process for the Preparation of Hydroxyl-Functionalized Polysiloxanes | LEIBNIZ-INSTITUT FUR KATALYSE E.V. (LIKAT) (DE) | 2019-10-24 | — | — | US | disclosed |
| EP-3336129-A1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYSILOXANES | Henkel AG & Co. KGaA (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-1114824-B1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6284907-B1 | REACTING HYDROGEN HALIDE WITH THE CORRESPONDING 1,3-DIHYDRO-1,1,3,3-TETRA(ORGANYL)DISILOXANES; CATALYST SELECTED FROM TRANSITION METALS OF THE 8TH SUBGROUP OF THE PERIODIC TABLE OF THE ELEMENTS, OR COMPOUNDS OR COMPLEXES | WACKER-CHEMIE GMBH (DE) | 2001-09-04 | — | — | US | disclosed |
| EP-1114824-A1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | Wacker-Chemie GmbH (DE) | 2001-07-11 | — | — | EP | disclosed |