SCHEMBL7765261

SCHEMBL7765261

CCCC[Si]1(c2ccccc2)CCC([C@H]2CC[C@H](CBr)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765275 1.00 KCNH2 (0.32) KCNH2
SCHEMBL7765269 1.00 KCNH2 (0.32) KCNH2
SCHEMBL7762435 0.96 KCNH2 (0.34) KCNH2
SCHEMBL7762442 0.96 KCNH2 (0.34) KCNH2
SCHEMBL7762449 0.96 KCNH2 (0.34) KCNH2
SCHEMBL7763769 0.92
SCHEMBL7763771 0.92
SCHEMBL7763775 0.92
SCHEMBL7760259 0.87 KCNH2 (0.34) KCNH2
SCHEMBL7763766 0.86 KCNH2 (0.36) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727428-B1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHINETSU CHEMICAL CO (JP) 2001-06-06 EP disclosed
US-5665271-A Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-09-09 US disclosed