SCHEMBL7765330

SCHEMBL7765330

[CH]=Cc1cncs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544073 0.74
Thiazole-5-Carbaldehyde SCHEMBL194323 0.74
SCHEMBL2405433 0.73 HDAC8 (0.36)
Thiazole-5-Carbaldehyde SCHEMBL31458553 0.72
Thiazole-5-Carbaldehyde SCHEMBL28152513 0.72
Thiazole-5-Carbaldehyde SCHEMBL27362558 0.70 PIM1 (0.40)
SCHEMBL17755831 0.69
SCHEMBL5904690 0.69
SCHEMBL2840435 0.69 HDAC8 (0.36)
SCHEMBL4395610 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025901-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND FUJIFILM CORPORATION (JP) 2024-01-25 US disclosed
US-20220213104-A1 METHOD FOR PRODUCING CYCLIC IMIDE COMPOUND, COMPOSITION, AND COMPOUND FUJIFILM CORPORATION (JP) 2022-07-07 US disclosed
EP-0723965-B1 NOVEL CEPHALOSPORIN DERIVATIVES MEIJI SEIKA KAISHA (JP) 2001-05-30 EP disclosed
US-5827845-A BACTERICIDES MEIJI SEIKA KAISHA, LTD. (JP) 1998-10-27 US disclosed
EP-0723965-A4 NOVEL CEPHALOSPORIN DERIVATIVE MEIJI SEIKA KAISHA (JP) 1997-02-12 EP disclosed
EP-0723965-A1 NOVEL CEPHALOSPORIN DERIVATIVE MEIJI SEIKA KAISHA LTD. (JP) 1996-07-31 EP disclosed
WO-1995009171-A1 NOVEL CEPHALOSPORIN DERIVATIVE MEIJI SEIKA KAISHA, LTD. (JP) 1995-04-06 WO disclosed
US-5234946-A Anticholesterol, antilipemic BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-10 US disclosed
EP-0318860-B1 SUBSTITUTED ALKYLAMINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-16 EP disclosed
EP-0318860-A2 Substituted alkylamine derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-06-07 EP disclosed