⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116997 | 0.88 | — | — | |
| SCHEMBL2744743 | 0.86 | — | — | |
| SCHEMBL7770154 | 0.86 | — | — | |
| SCHEMBL2744844 | 0.84 | — | — | |
| SCHEMBL2744531 | 0.82 | — | — | |
| SCHEMBL2744695 | 0.80 | — | — | |
| SCHEMBL2744511 | 0.80 | — | — | |
| SCHEMBL2744506 | 0.80 | — | — | |
| SCHEMBL12504587 | 0.79 | — | — | |
| SCHEMBL2744686 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114824-B1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6284907-B1 | REACTING HYDROGEN HALIDE WITH THE CORRESPONDING 1,3-DIHYDRO-1,1,3,3-TETRA(ORGANYL)DISILOXANES; CATALYST SELECTED FROM TRANSITION METALS OF THE 8TH SUBGROUP OF THE PERIODIC TABLE OF THE ELEMENTS, OR COMPOUNDS OR COMPLEXES | WACKER-CHEMIE GMBH (DE) | 2001-09-04 | — | — | US | disclosed |
| EP-1114824-A1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | Wacker-Chemie GmbH (DE) | 2001-07-11 | — | — | EP | disclosed |
| EP-1110965-A2 | Process for preparing 1,3-dihalo-1,1,3,3-tetra(organyl)disiloxanes | Wacker-Chemie GmbH (DE) | 2001-06-27 | — | — | EP | disclosed |
| US-5760210-A | Process for the preparation of ribonucleotide reductase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5595979-A | Method of treating a neoplastic disease state by conjunctive therapy with 2'-fluoromethylidene derivatives and radiation or chemotherapy | MERRELL PHARMACEUTICALS INC. (US) | 1997-01-21 | — | — | US | disclosed |
| US-5589587-A | Process for the preparation of ribonucleotide reductase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0738273-A1 | MONOHYDRATE OF (E)-2'-DEOXY-2'-(FLUOROMETHYLENE)CYTIDINE | MERRELL PHARMACEUTICALS INC. (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5508393-A | Process for the preparation of ribonucleotide reductase inhibitors | HOESCHST MARION ROUSSEL, INC. (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1996001638-A1 | METHOD OF TREATING A NEOPLASTIC DISEASE STATE BY CONJUNCTIVE THERAPY WITH 2'-FLUOROMETHYLIDENE DERIVATIVES AND RADIATION OR CHEMOTHERAPY | HOECHST MARION ROUSSEL, INC. (US) | 1996-01-25 | — | — | WO | disclosed |
| WO-1995018815-A1 | MONOHYDRATE OF (E)-2'-DEOXY-2'-(FLUOROMETHYLENE)CYTIDINE | MERRELL PHARMACEUTICALS INC. (US) | 1995-07-13 | — | — | WO | disclosed |