Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 18/20 | 1.00 |
| ▸ | DRD2 | P14416 | 17/20 | 1.00 |
| ▸ | DRD4 | P21917 | 14/20 | 0.76 |
| ▸ | HTR1A | P08908 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | HTR2A | P28223 | 1/20 | 0.76 |
| ▸ | HTR2C | P28335 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7762608 | 0.99 | DRD3 (0.98) | DRD3DRD2DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL7538290 | 0.98 | DRD3 (0.96) | DRD3DRD2DRD4HTR1AMEN1 | |
| SCHEMBL7344083 | 0.94 | DRD3 (1.00) | DRD3DRD2DRD4HTR1AMEN1 | |
| SCHEMBL30298993 | 0.94 | DRD3 (1.00) | DRD3DRD2DRD4HTR1AMEN1 | |
| SCHEMBL7766329 | 0.94 | DRD3 (0.89) | DRD3DRD2DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL7762622 | 0.94 | DRD3 (0.88) | DRD3DRD2DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL7421290 | 0.89 | DRD3 (0.81) | DRD3DRD2DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL7421291 | 0.89 | DRD3 (0.81) | DRD3DRD2DRD4HTR1AMEN1 | |
| SCHEMBL7343763 | 0.89 | DRD3 (0.89) | DRD3DRD2DRD4HTR1AMEN1 | |
| SCHEMBL7762650 | 0.86 | DRD3 (1.00) | DRD3DRD2DRD4HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873329-B1 | NOVEL N-AMINOALKYLFLUORENECARBOXAMIDES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2001-06-06 | — | — | EP | claimed |
| EP-0873329-A1 | NOVEL N-AMINOALKYLFLUORENECARBOXAMIDES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997010229-A1 | NOVEL N-AMINOALKYLFLUORENECARBOXAMIDES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1997-03-20 | — | — | WO | disclosed |