Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770010 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7768001 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7770008 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7765419 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7767346 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7767985 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7762660 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7762762 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7766304 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7770045 | 1.00 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718281-B1 | CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NISSIN FOOD PRODUCTS LTD (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0718281-A1 | CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |