SCHEMBL77660

SCHEMBL77660

O=C=Nc1ccc(Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
MAPK1 P28482 2/20 0.58
CYP3A4 P08684 4/20 0.56
TSHR P16473 2/20 0.56
TRPA1 O75762 1/20 0.43
LMNA P02545 1/20 0.42
CYP2A6 P11509 1/20 0.42
HTR3E A5X5Y0 2/20 0.41
HTR3B O95264 2/20 0.41
HTR3A P46098 2/20 0.41
HTR3D Q70Z44 2/20 0.41
HTR3C Q8WXA8 2/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
PLAU P00749 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP1A2 P05177 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11551012 0.93 TDP1 (0.52) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL27995745 0.93 TDP1 (0.52) TDP1MAPK1CYP3A4TSHRTRPA1
Dimethylamine SCHEMBL11802975 0.91 CYP3A4 (0.54) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL8093595 0.89 TDP1 (0.48) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL10534838 0.87 MAPK1 (0.47) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL15430 0.86 CYP3A4 (0.70) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL2782331 0.84 TDP1 (0.53) TDP1MAPK1CYP3A4TSHRTRPA1
Pyridine SCHEMBL28157864 0.84 TDP1 (0.44) TDP1MAPK1CYP3A4TSHRTRPA1
Tetrahydrofuran SCHEMBL28101791 0.84 MAPK1 (0.44) TDP1MAPK1CYP3A4TSHRTRPA1
Chlorobenzene SCHEMBL27462549 0.83 TSHR (0.50) TDP1MAPK1CYP3A4TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5303 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122057276-A Environment-friendly pretreatment device for p-chlorophenyl isocyanate production sewage 濮阳市宏大圣导新材料有限公司 2026-05-19 CN claimed
US-12509547-B2 Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component BASF SE (DE) 2025-12-30 US claimed
CN-119819277-B Beta-cyclodextrin derivative chiral stationary phase based on BINAM and preparation method and application thereof 昆明医科大学 2025-05-27 CN claimed
CN-119977025-A Automatic wastewater treatment device and method for p-chlorophenyl isocyanate processing 濮阳市宏大圣导新材料有限公司 2025-05-13 CN claimed
CN-119819277-A Beta-cyclodextrin derivative chiral stationary phase based on BINAM and preparation method and application thereof 昆明医科大学 2025-04-15 CN claimed
CN-119662137-A Easy-to-detach adhesive tape, preparation method and application of easy-to-detach adhesive tape in die-cut piece 赛维精密科技(广东)有限公司 2025-03-21 CN claimed
CN-119398807-A Vehicle health assessment method, device and system based on artificial intelligence and storage medium 广东唯普汽车科技股份有限公司 2025-02-07 CN claimed
CN-119161580-A Amide group-containing polydisulfide degradable high polymer material and preparation method thereof 衢州化工新材料创新研究院 2024-12-20 CN claimed
CN-115557936-B Preparation method and application of pomalidomide derivative serving as feed additive 河南湾流生物科技有限公司 2024-12-06 CN claimed
EP-4468851-A1 METHOD AND INSTALLATION FOR WORKING A PLOT OF LAND WITH AT LEAST ONE REPLENISHED AGRICULTURAL ROBOT Kuhn SAS (FR) 2024-12-04 EP claimed
EP-0159388-A2 Preparation of nuclear chlorinated compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1985-10-30 EP claimed
US-4470930-A Preparation of nuclear chlorinated aromatic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1984-09-11 US claimed
US-4359426-A Process for the production of aromatic isocyanates containing aromatically bound sulfochloride groups BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US claimed
EP-0034711-A2 Process for preparing aromatic isocyanates with aromatically bound sulfochloride groups BAYER AG (DE) 1981-09-02 EP claimed
WO-1979000858-A1 DIARYL SUBSTITUTED PYROZOLINE CARBOXANILIDES,PROCESSES FOR PREPARING THEM,INSECTICIDAL COMPOSITIONS AND USES THEREOF,AND INTERMEDIATES THEREFOR ICI LTD (GB) 1979-11-01 WO claimed
EP-0004733-A2 Diaryl substituted pyrazoline carboxanilides, processes for preparing them, insecticidal compositions and uses thereof, and intermediates therefor IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-10-17 EP claimed
US-4117009-A EXTRACTION WITH A SELECTIVE SOLVENT GAF CORPORATION (US) 1978-09-26 US claimed
US-3976610-A Acrylate rubber vulcanizable compositions THE B. F. GOODRICH COMPANY (US) 1976-08-24 US claimed
US-3948941-A NITRILE, FROM CARBOXYLIC ANHYDRIDES AND ISOCYANATES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-04-06 US claimed
US-3940246-A Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor CIBA-GEIGY AG (CH) 1976-02-24 US claimed