SCHEMBL7766103

SCHEMBL7766103

CCC(C)CC(C)(O)CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.56
CHRM1 P11229 1/20 0.56
TBXA2R P21731 1/20 0.56
ADRA1A P35348 1/20 0.56
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 2/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.34
CPT2 P23786 2/20 0.34
KDM4E B2RXH2 1/20 0.34
FFAR1 O14842 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACLY P53396 1/20 0.32
HSPD1 P10809 1/20 0.32
BLM P54132 1/20 0.32
HSPE1 P61604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14973297 0.81 KDM4E (0.45) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL28715378 0.80 HMGCR (0.64) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL4988024 0.78 HMGCR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL1818224 0.78 HMGCR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL1814281 0.78 HMGCR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL3993645 0.78 HMGCR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL1817097 0.78 HMGCR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL724008 0.76 HMGCR (0.64) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL31021334 0.75 HMGCR (0.34) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL14672450 0.75 TSHR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303797-B1 EFFECTIVE AGAINST RESISTANT SPECIES BANYU PHARMACEUTICAL CO., LTD. (JP) 2001-10-16 US disclosed
EP-1104757-A1 SESTERTERPENE DERIVATIVES EXHIBITING ANTIFUNGAL ACTIVITIES BANYU PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed