SCHEMBL7766289

SCHEMBL7766289

CCCCC[SiH]1CCC(CCCC[C@H]2CC[C@H](c3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.32
GAA P10253 1/20 0.32
CYP2C9 P11712 1/20 0.31
CCR2 P41597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7766292 1.00 MEN1 (0.36) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL7766296 1.00 MEN1 (0.36) MEN1KMT2AMAPTGAACYP2C9
SCHEMBL7759601 0.96 MEN1 (0.32) MEN1KMT2AMAPTCYP2C9
SCHEMBL7759606 0.96 MEN1 (0.32) MEN1KMT2AMAPTCYP2C9
SCHEMBL7767847 0.96 MEN1 (0.32) MEN1KMT2A
SCHEMBL7767851 0.96 MEN1 (0.32) MEN1KMT2A
SCHEMBL7762666 0.92 CYP2C9 (0.32) MEN1KMT2AMAPTCYP2C9
SCHEMBL7762676 0.92 CYP2C9 (0.32) MEN1KMT2AMAPTCYP2C9
SCHEMBL7762672 0.92 CYP2C9 (0.32) MEN1KMT2AMAPTCYP2C9
SCHEMBL7767219 0.89 MEN1 (0.34) MEN1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727428-B1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHINETSU CHEMICAL CO (JP) 2001-06-06 EP disclosed
US-5665271-A Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-09-09 US disclosed
EP-0727428-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-08-21 EP disclosed